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A 2018 systematic review and network meta-analysis of 50 trials involving 12 different psychosocial interventions for amphetamine, methamphetamine, or cocaine addiction found that combination therapy with both contingency management and community reinforcement approach had the highest efficacy (i.e., abstinence rate) and acceptability (i.e ...
The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [ 96 ] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [ 97 ]
A tag throw by Helena Douglas and Leifang against Ayane in Dead or Alive Ultimate. The Dead or Alive series focuses on fast-paced gameplay in a three-dimensional playing field. . Like other modern fighting games that attempt to emulate real life martial arts, DOA's input system is designed so controls correspond to the game character's actions; if the character moves forward with a punch, the ...
When in hybrid mode, the vehicle has a combined city/highway rating of 50 mpg ‑US (4.7 L/100 km; 60 mpg ‑imp), the same as the conventional third-generation Prius. [51] According to Toyota the Prius plug-in is expected to be rated in Europe at 2.10 L/100 km (112 mpg ‑US ; 135 mpg ‑imp ) equivalent, with CO 2 emissions of 49 g/km (2.8 oz ...
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