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Off-target genome editing refers to nonspecific and unintended genetic modifications that can arise through the use of engineered nuclease technologies such as: clustered, regularly interspaced, short palindromic repeats ()-Cas9, transcription activator-like effector nucleases (), meganucleases, and zinc finger nucleases (ZFN). [1]
X is a 2022 American slasher film written, directed, produced and edited by Ti West.It stars Mia Goth in dual roles: a young woman named Maxine, and an elderly woman named Pearl.
Fifty Shades of Grey is a 2011 erotic romance novel by British author E. L. James. [1] It became the first installment in the Fifty Shades novel series that follows the deepening relationship between a college graduate, Anastasia Steele, and a young business magnate, Christian Grey.
NATO was established on 4 April 1949 via the signing of the North Atlantic Treaty (Washington Treaty). The 12 founding members of the Alliance were: Belgium, Canada, Denmark, France, Iceland, Italy, Luxembourg, the Netherlands, Norway, Portugal, the United Kingdom, and the United States.
[1] [2]: vii Although girls typically begin the process of puberty at age 10 or 11, and boys at age 11 or 12, [3] psychiatric diagnostic criteria for pedophilia extend the cut-off point for prepubescence to age 13. [4] People with the disorder are often referred to as pedophiles (or paedophiles). Pedophilia is a paraphilia.
ZCTAs or ZIP Code Tabulation Areas are the census equivalent of ZIP codes used for statistical purposes. The reason why regular ZIP codes are not used is because they are defined by routes rather than geographic boundaries. Thus, they have the tendency to overlap and otherwise create difficulties.
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