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Sildenafil, sold under the brand name Viagra, among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4][8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]
The U.S. Census Bureau estimated that the population of Florida was 21,477,737 on July 1, 2019, a 14.24% increase since the 2010 United States census. [153] The population of Florida in the 2010 census was 18,801,310. [154] Florida was the seventh fastest-growing state in the U.S. in the 12-month period ending July 1, 2012. [155]
The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [ 96 ] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [ 97 ]
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