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Off-target genome editing refers to nonspecific and unintended genetic modifications that can arise through the use of engineered nuclease technologies such as: clustered, regularly interspaced, short palindromic repeats ()-Cas9, transcription activator-like effector nucleases (), meganucleases, and zinc finger nucleases (ZFN). [1]
A 1992 World Health Organization report described normal human semen as having a volume of 2 mL or greater, pH of 7.2 to 8.0, sperm concentration of 20×10 6 spermatozoa/mL or more, sperm count of 40×10 6 spermatozoa per ejaculate or more, and motility of 50% or more with forward progression (categories a and b) of 25% or more with rapid ...
The Las Vegas Strip is a stretch of Las Vegas Boulevard immediately south of the city of Las Vegas in Clark County, Nevada.The Strip is known for its concentration of casinos and resort hotels, including the 43-story Mandalay Bay southwest of its intersection with Mandalay Bay Road, in the unincorporated town of Paradise.
[1] [2]: vii Although girls typically begin the process of puberty at age 10 or 11, and boys at age 11 or 12, [3] psychiatric diagnostic criteria for pedophilia extend the cut-off point for prepubescence to age 13. [4] People with the disorder are often referred to as pedophiles (or paedophiles). Pedophilia is a paraphilia.
ZCTAs or ZIP Code Tabulation Areas are the census equivalent of ZIP codes used for statistical purposes. The reason why regular ZIP codes are not used is because they are defined by routes rather than geographic boundaries. Thus, they have the tendency to overlap and otherwise create difficulties.
The timetable for the October 2022 leadership election was much shorter than the July one. An expedited process was set out; candidates were required to obtain 100 nominations from fellow Conservative MPs before 2 pm on 24 October, and an MPs' ballot followed by a online members' ballot was to be held shortly thereafter if more than one candidate received more than 100 nominations.
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