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Fentanyl is a highly potent synthetic piperidine opioid primarily used as an analgesic.It is 20 to 40 times more potent than heroin and 100 times more potent than morphine; [9] its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries.
The protonated form of methadone takes on an extended conformation, while the free base is more compact. In particular, it was found that there is an interaction between the tertiary amine and the carbonyl carbon of the ketone function (R 3 N ••• >C=O) that limits the molecule's conformation freedom, though the distance (291 pm by X-ray ...
Original logo (used until 1993, but carried by stores until 1997) Costco Wholesale Corporation is an American multinational corporation which operates a chain of membership-only big-box warehouse club retail stores. [4] As of 2021, Costco is the third-largest retailer in the world [5] and is the world's largest retailer of choice and prime beef ...
On March 19, 2024, Subway signed a 10-year deal with PepsiCo that begins on January 1, 2025, ending the restaurant chain's partnership with The Coca-Cola Company that was first signed in 2003 and went into effect in 2005. [45] [46] Subway's international locations had already gone back to serving Pepsi products in 2018. [46]
Betelgeuse is the brightest near-infrared source in the sky with a J band magnitude of −2.99; [95] only about 13% of the star's radiant energy is emitted as visible light. If human eyes were sensitive to radiation at all wavelengths, Betelgeuse would appear as the brightest star in the night sky.
A coup d'état (/ ˌ k uː d eɪ ˈ t ɑː / ⓘ; French: [ku deta]; lit. ' stroke of state '), [1] or simply a coup, is typically an illegal and overt attempt by a military organization or other government elites to unseat an incumbent leadership.
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