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12929 Ensembl ENSG00000099942 ENSMUSG00000006134 UniProt P46109 P47941 RefSeq (mRNA) NM_005207 NM_001277231 NM_007764 RefSeq (protein) NP_005198 NP_001264160 NP_031790 Location (UCSC) Chr 22: 20.92 – 20.95 Mb Chr 16: 17.27 – 17.31 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Crk-like protein is a protein that in humans is encoded by the CRKL gene. Function
Adapter molecule crk is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. This protein has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction.
MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene ...
In fact, 20% of voters in key battleground states identified crypto as a major issue in the 2024 election season according to a recent survey by Digital Currency Group.
Clark International Airport ( IATA: CRK, ICAO: RPLC ), known as Diosdado Macapagal International Airport from 2003 to 2014, is an international airport covering portions of the cities of Angeles and Mabalacat within the Clark Freeport Zone in the province of Pampanga, Philippines. It is located 80 kilometers (50 mi) [6] northwest of Manila.
The protein encoded by this gene is a human guanine nucleotide releasing protein for Ras protein. It belongs to the adaptor-type Src homology (SH)2-containing molecules. Src homology 2 domains are globular protein modules present in a large variety of functionally distinct proteins. They mediate binding events that control the activity and ...
Cookie Run: Kingdom is an action role-playing gacha game by Devsisters and the sixth game in the Cookie Run series. It was announced on November 28, 2020 and released worldwide on January 19, 2021 on Android and iOS. On July 12, 2023, it was released on Google Play Games on PC . The game features new Cookies and over 200 levels.
ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells.
View/Edit Mouse. Dedicator of cytokinesis protein 5 ( Dock5) is a large (~180 kDa) protein encoded in the human by the DOCK5 gene, involved in intracellular signalling networks. [5] It is a member of the DOCK-A subfamily of the DOCK family of guanine nucleotide exchange factors (GEFs) which function as activators of small G-proteins. [6]
Neural precursor cell expressed developmentally down-regulated protein 9 ( NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. [5] NEDD-9 is also known as enhancer of filamentation 1 ( EF1 ), CRK-associated substrate-related protein ( CAS-L ), and Cas scaffolding protein family member 2 ( CASS2 ).